Chloride is the major anion seen in both, the blood and the extracellular fluid.
According to The Vitamins and Nutrition Center, chloride, potassium and calcium are among the most important serum electrolytes. Anion is nothing, but the negatively charged portion of some substances like sodium chloride (NaCl) or table salt, on getting dissolved in liquid.
Maximum of chloride ions we get by the food we eat. The normal values increase as we consume more of canned foods rich in salt.Helps in keeping the acid-base balance in the body. Sea water and human fluids has the same concentration of chloride ions.
Chloride ion balance is regulated and maintained by the body. Any significant decrease or increase may have harmful or fatal consequences.During digestion, the intestines absorb the chloride. Excess chloride after the digestion process, gets excreted in the urine. Kidneys control the chloride levels in the blood. Abnormal elevation of chloride may be found in diarrhea, hyperparathyroidism and kidney diseases.