What is Progressive Supranuclear Palsy?


What is progressive supranuclear palsy?

Progressive supranuclear palsy is a rare brain disorder disease. The disorder causes deterioration of cells in areas of your brain that controls thinking and movement. Thus, having the disorder may lead to serious problems with walking, balancing and eye movements.

The disorder may worsen over time and in the end threaten your life. Complications such as pneumonia may develop afterwards.

Currently, progressive supranuclear palsy is incurable.


The main symptoms of the disorder include:

  • Loss of balance while walking
  • Have difficulties looking downward
  • Have swallowing and speech problems
  • Depression and anxiety
  • Have trouble in reasoning, thinking and decision-making
  • Sleep disturbances
  • Stiffness and awkward movements
  • Have no interests in pleasurable activities


Why progressive supranuclear palsy occurs remains a problem to be solved. Currently, researchers now have found that people with the disorder have abnormal amounts of a protein called tau.

Although progressive supranuclear palsy rarely happens within a family. Whether the disease has a genetic link is unclear.


Given the fact that the disease has no cure for now, treatment focuses on managing the symptoms.

Keywords: progressive supranuclear palsy; incurable; causes; symptoms; treatment; Q&A

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