What Is Plasmablastic Lymphoma and Its Survival Rate?

Q:
What is plasmablastic lymphoma and its survival rate?
A:
Plasmablastic lymphoma is an aggressive form of non-Hodgkin lymphoma. It is a lymphoma with plasmablastic morphology predominantly associated with HIV infection. The condition most commonly occurs in the oral cavity and jaw, though it can appear in many other parts of the body such as the gastrointestinal tract, lymph nodes, and skin.

Signs and Symptoms

  • Disseminated bone involvement
  • Drenching night sweats
  • Fatigue
  • Fever (for no known reason)
  • Pain in the chest, abdomen, or bones (for no known reason)
  • Painless swelling in the lymph nodes
  • Skin rash or itchy skin
  • Weight loss (for no known reason)
It mostly happens in adults with a 50 years median age and is rare in children. Its exact underlying cause is still unkown, and there is currently no standard therapy for the disease. The average survival from diagnosis is less than one year.
Keywords: plasmablastic lymphoma

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