What is Mucosal Melanoma?

what is mucosal melanoma?

Mucosal melanoma is a rare type of melanoma that occurs in the mucous membranes of areas inside of your body. Though melanoma will usually cause pigmentation, mucosal melanomas are not always pigmented. However, mucosal melanoma is very rare, with 1 in 100 cases of melanomas is of the mucosal variety.

Mucosal melanoma can appear in multiple areas in your body such as eyes, mouth, head, neck, respiratory tract, gastrointestinal tract, vagina and vulva and anus.


The symptoms vary based on the location of the mucosal melanoma. Some symptoms of mucosal melanoma can include:

  • head and neck mucosal melanoma – obstruction of the nasal cavity, nose bleeding, not being able to smell, the presence of the lump, ulcers, dentures that stop fitting properly
  • anus or rectal mucosal melanoma – bleeding, plain in the areas. diarrhea, constipation, the presence of a lump
  • vaginal mucosal melanoma – itching, vulvar discoloration, vaginal discharge, a noticeable lump


Surgery serves as the primary treatment option when the melanoma is still small. With imaging tests, the doctors can draw excisional margins and eventually cut out the tumor.

However, when the tumor is in delicate areas such as head and neck areas, surgery may not be an option. Chemotherapy, radiotherapy, immunotherapy and targeted therapy are the main alternatives under such circumstances.

If you are not sure about your treatments, please go to see a doctor for professional help.

Keywords: Mucosal Melanoma; symptoms; treatment; Q&A

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