What Are the Symptoms of Amyopathic Dermatomyositis?

What are the symptoms of amyopathic dermatomyositis?

Amyopathic dermatomyositis refers to a type of dermatomyositis with only or mainly skin lesions. Patients with amyopathic dermatomyositis usually have no muscle involvement. And there will be no inflammatory myopathy for 2 years after skin changes, during which the level of muscle enzymes (creatine kinase and aldolase) remains normal.

However, amyopathic dermatomyositis has a high incidence of malignant tumors and is associated with neoplastic connective tissue disease.


Signs and symptoms of amyopathic dermatomyositis may include:

  • edematous purple spots around the eyelids;
  • heterochromatosis erythema in the neck, shoulders, upper chest, forearm and upper arm;
  • Gottron papules and Gottron signs;
  • telangiectasia at the nail fold (a contraction of telangiectasia)
  • no muscle involvement, including muscle inflammation, weakness and pain;
  • pulmonary lesions, for example, interstitial lung disease (ILD) is a relatively common and serious clinical manifestation, mainly characterized by dry cough, exertional dyspnea, and both lungs examined with blasting sounds.


Keyword: amyopathic dermatomyositis symptoms.

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