What Are the Causes of Hemophilia?

Q:
What are the causes of hemophilia?

A:
Hemophilia is a type of blood disease that is inherited or caused by gene mutations. Normal body can stop the bleeding by pooling blood cells together to form a clot. If there is a deficiency in one of these clotting factors, hemophilia occurs.

There are different types of hemophilia. Most cases are inherited. The X chromosome is the place where the genetic defect occurs, which leads to hemophilia. However, approximately 30% of patients with hemophilia don’t have family history.

In those patients who have no family history, the disease is caused by genetic mutations.

Another type of hemophilia is acquired hemophilia. The disease is rare and usually associated with pregnancy, cancer, multiple sclerosis and autoimmune conditions.

 

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