What Are the Basics of Liposarcoma?

What is liposarcoma?

Liposarcoma is a malignant tumor that arises in fat cells in deep soft tissue. It is one type of soft tissue sarcomas, mainly affecting middle-age people at sites such as the thigh, gluteal region, retroperitoneum, and leg and shoulder area.

Liposarcoma can be categorized into following three families:

  • well-differentiated and/or dedifferentiated (50%)
  • myxoid and/or round cell (40%)
  • pleomorphic (10%)

Each of the family has its own specific biology and risk of recurrence or spread, as such, each requires its own unique treatment.

What are the signs and symptoms of liposarcoma?

Signs and symptoms of liposarcomas vary depending on the location of the tumor and the extent to which it has spread in the body.

Symptoms and signs that may occur later in the disease can include

  • painful swelling and/or a growing lump under the skin;
  • numbness;
  • enlargement of varicose veins;
  • fatigue and/or weakness, especially of the affected limb;
  • abdominal pain, and/or blood in the stool (these symptoms are more likely to develop in patients
  • with liposarcoma the forms in the abdomen);
  • chest pain;
  • urinary difficulty and/or pain;
  • difficulty swallowing;
  • nausea;
  • vomiting;
  • decreased range of motion in the limbs.

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