Vanillylmandelic Acid (VMA) – Reference Values

The vanillylmandelic acid range of people is varies by age. Following are the specific number:

<1 year: <25.0 mg/g creatinine
1 year: <22.5 mg/g creatinine
2-4 years: <16.0 mg/g creatinine
5-9 years: <12.0 mg/g creatinine
10-14 years: <8.0 mg/g creatinine
≥15 years (adults): <8.0 mg/24 hours

Since the VMA test is sensitive to many outside influences, and neuroblastomas and pheochromocytomas are rare, the false-positive rate for this test is high – greater than 15%.

When a person has large amounts of VMA in his or her urine, it is not diagnostic of a condition; it is an indication that further investigation is necessary.

If a child or adult is being treated for a neuroblastoma or pheochromocytoma, then decreasing VMA concentrations indicate a response to treatment; stable or increasing levels indicate that the treatment is not effective.

If a VMA concentration is initially normal and then increases in a person who has had a previous neuroblastoma or pheochromocytoma, then it is likely that the tumor is recurring.

Keywords: VMA; Vanillylmandelic Acid; urine VMAU

Leave a Reply