Ticlopidine helps to prevent platelets in your blood from sticking together and forming a blood clot. An unwanted blood clot can occur with certain heart or blood vessel conditions.
Ticlopidine is used to prevent blood clots after a recent heart attack or stroke, and in people who have had a stent placed in the arteries that supply blood to the heart.
Ticlopidine may also be used for other purposes not listed in this medication guide.
Before taking this medicine
You should not use ticlopidine if you are allergic to ticlopidine, or if you have:
- severe liver disease;
- any active bleeding such as a stomach ulcer or bleeding in the brain (such as from a head injury); or
- a blood cell disorder such as anemia (lack of red blood cells) or low levels of platelets (cells that help your blood clot).
To make sure ticlopidine is safe for you, tell your doctor if you have:
- high cholesterol or triglycerides;
- a stomach ulcer;
- stomach or intestinal bleeding;
- a history of surgery, injury, or medical emergency;
- liver disease; or
- kidney disease.
Ticlopidine is not expected to be harmful to an unborn baby. However, aspirin is sometimes given with ticlopidine, and aspirin can cause bleeding when it is taken during the last 3 months of pregnancy. Aspirin can also cause side effects in a newborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether ticlopidine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some of the side effects of ticlopidine can occur in the first few days of taking ticlopidine, or after several weeks of treatment.
Call your doctor at once if you have:
- any bleeding that will not stop;
- severe or ongoing diarrhea;
- pink or brown urine;
- low blood cell counts–fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed;
- liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- signs of stomach bleeding–bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
- signs of a serious blood-clotting problem–pale skin, purple spots under your skin or on your mouth, problems with speech, weakness, seizures (convulsions), dark urine, jaundice.
Common side effects may include:
- low blood cell counts;
- diarrhea, nausea, vomiting;
- upset stomach; or