Effectiveness
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The effectiveness ratings for ROSE HIP are as follows:
Possibly effective for…
- Osteoarthritis. Most research shows that taking a specific rose hip product (LitoZin/i-flex, Hyben Vital) by mouth twice daily for 3-4 months reduces pain and stiffness and improves function in people with osteoarthritis.
Insufficient evidence to rate effectiveness for…
- Obesity. Early research shows that taking rose hip powder mixed with apple juice does not affect weight or blood sugar levels in people who are obese. But it might slightly reduce cholesterol and blood pressure.
- Rheumatoid arthritis. Early research shows that taking a specific rose hip product (LitoZin/i-flex, Hyben Vital) by mouth improves some symptoms of rheumatoid arthritis.
- Stretch marks (striae gravidarum). Early research shows that applying a specific cream containing rose hip oil and other ingredients (Velastisa Antiestrías, ISDIN) to the skin at least twice daily during pregnancy reduces the severity of stretch marks. It also might reduce the chance of getting stretch marks in women who didn’t have stretch marks before becoming pregnant.
- Boosting the immune system.
- Diarrhea.
- Fever.
- Infections.
- Preventing and treating colds.
- Stomach irritations.
- Other conditions.
More evidence is needed to rate rose hip for these uses.
Dose
ADULTS
- For osteoarthritis: Five capsules containing a total of 2.5 grams of rose hip powder (LitoZin/i-flex, Hyben Vital) has been taken twice daily for 3 months.
Safety Concerns
There is not enough reliable information about the safety of applying rose hip to the skin.
Special precautions & warnings:
Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking rose hip by mouth as a medicine during pregnancy or breast feeding. Stay on the safe side and avoid using amounts larger than those found in food. There is also not enough reliable information about the safety of rose hip when applied to the skin during pregnancy or breast feeding.
Diabetes: The vitamin C in rose hip might affect the control of diabetes, but not all experts agree on this.
Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency): Large amounts of the vitamin C in rose hip might increase the risk of complications.
Bleeding conditions: Rugosin E, a chemical found in rose hip, might slow blood clotting. Taking rose hip might increase the risk of bleeding in people with bleeding disorders.
Kidney stones: Large amounts of the vitamin C in rose hip might increase the chance of getting kidney stones.
Iron-related disorders such as hemochromatosis, thalassemia, or anemia: Use rose hip with caution if you have any of these conditions. The vitamin C in rose hip can increase iron absorption, which could make your condition worse.
Heart attack (myocardial infarction): Rose hip contains rugosin E. Rugosin E might cause blood clots. If you’ve had a heart attack, taking rose hip might increase the chance of blood clots or another heart attack.
Sickle cell disease: It is rare, but the vitamin C in rose hip might make blood more acidic. This could bring on a sickle cell crisis. It’s best to avoid use.
Stroke: Rose hip contains rugosin E. Rugosin E might cause blood clots. If you’ve had a stroke, taking rose hip might increase the chance of blood clots or another stroke.
Blood clots in legs (deep vein thrombosis) or lungs (pulmonary embolism): Rose hip contains rugosin E. Rugosin E might cause blood clots. If you’ve had blood clots in your legs or lungs before, taking rose hip might increase the chance of another clot.
Interaction with medication
- Aluminum
- Aluminum is found in most antacids. Rose hips contain vitamin C. Vitamin C can increase how much aluminum the body absorbs. But it isn’t clear if this interaction is a big concern. Take rose hip two hours before or four hours after antacids.
- Estrogens
- Rose hip contains a large amount of vitamin C. Vitamin C can increase how much estrogen the body absorbs. Taking rose hip along with estrogen can increase the effects and side effects of estrogens.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
- Fluphenazine (Prolixin)
- Rose hip contains vitamin C. Large amounts of vitamin C might increase how quickly the body gets rid of fluphenazine (Prolixin). Taking rose hip along with fluphenazine (Prolixin) might decrease the effectiveness of fluphenazine (Prolixin).
- Lithium
- Rose hip might have an effect like a water pill or “diuretic.” Taking rose hip might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.
- Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
- Rose hip contains a chemical that might cause blood to clot. Taking rose hip along with medications that slow clotting might decrease how well these medications work.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.
- Warfarin (Coumadin)
- Warfarin (Coumadin) is used to slow blood clotting. Rose hip contains vitamin C. Large amounts of vitamin C might decrease the effectiveness of warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the chance of clotting. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.
- Aspirin
- The body breaks down aspirin to get rid of it. Rose hip contains large amounts of vitamin C. Large amounts of vitamin C might decrease the breakdown of aspirin. Taking large amount of rose hip along with aspirin might increase the effects and side effects of aspirin. Do not take large amounts of vitamin C if you take large amounts of aspirin.
- Choline Magnesium Trisalicylate (Trilisate)
- Rose hip contains vitamin C. Vitamin C might decrease how quickly the body gets rid of choline magnesium trisalicylate (Trilisate). But it is not clear if this interaction is a big concern.
- Salsalate (Disalcid)
- Rose hip contains vitamin C. Vitamin C might decrease how quickly the body gets rid of salsalate (Disalcid). Taking rose hip along with salsalate (Disalcid) might increase the effects and side effects of salsalate.
