Risedronate: Uses, Side Effects

Risedronate is a bisphosphonate medicine
that alters bone formation and breakdown in the body. This can slow bone loss
and may help prevent bone fractures.

Risedronate is used to treat osteoporosis
caused by menopause, steroid use, or gonadal failure. risedronate is for use
when you have a high risk of bone fracture due to osteoporosis.

Risedronate is also used to treat Paget’s
disease of bone.

Risedronate may also be used for purposes
not listed in this medication guide.

Important Information

You should not take risedronate if you have
problems with your esophagus, or low levels of calcium in your blood.

Do not take risedronate if you cannot sit
upright or stand for at least 30 minutes after taking the medicine.

Risedronate can cause serious problems in
the stomach or esophagus. Stop using risedronate and call your doctor at once
if you have chest pain, new or worsening heartburn, or pain when swallowing.

Also call your doctor if you have muscle
spasms, numbness or tingling (in hands and feet or around the mouth), new or
unusual hip pain, or severe pain in your joints, bones, or muscles.

Before taking this medicine

You should not take risedronate if you are
allergic to it, or if you have:

  • low levels of calcium in your blood (hypocalcemia); or
  • problems with the muscles in your esophagus (the tube that connects
    your mouth and stomach).

Do not take risedronate if you cannot sit
upright or stand for at least 30 minutes. Risedronate can cause serious
problems in the stomach or esophagus. You must stay upright for at least 30
minutes after taking risedronate.

To make sure risedronate is safe for you,
tell your doctor if you have ever had:

  • trouble swallowing;
  • problems with your stomach or digestion;
  • hypocalcemia;
  • a dental problem (you may need a dental exam before you begin taking
    risedronate);
  • kidney disease; or
  • any condition that makes it hard for your body to absorb nutrients
    from food (malabsorption).

In rare cases, this medicine may cause bone
loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or
swollen gums, loose teeth, or slow healing after dental work. The longer you
use risedronate, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely
if you have cancer or received chemotherapy, radiation, or steroids. Other risk
factors include blood clotting disorders, anemia (low red blood cells), and a preexisting
dental problem.

Talk with your doctor about the risks and benefits
of using this medication.

It is not known whether this medicine will
harm an unborn baby. Tell your doctor if you are pregnant or plan to become
pregnant.

It is not known whether risedronate passes
into breast milk or if it could harm a nursing baby. Tell your doctor if you
are breast-feeding a baby.

Side effects

Get emergency medical help if you have
signs of an allergic reaction (hives, difficult breathing, swelling in your
face or throat) or a severe skin reaction (fever, sore throat, burning in your
eyes, skin pain, red or purple skin rash that spreads and causes blistering and
peeling).

Stop using risedronate and call your doctor
at once if you have:

  • chest pain, new or worsening heartburn;
  • difficulty or pain when swallowing;
  • pain or burning under the ribs or in the back;
  • severe heartburn, burning pain in your upper stomach, or coughing up
    blood;
  • new or unusual pain in your thigh or hip;
  • jaw pain, numbness, or swelling;
  • severe joint, bone, or muscle pain; or
  • low calcium levels–muscle spasms or contractions, numbness or
    tingly feeling (around your mouth, or in your fingers and toes).

Common side effects may include:

  • heartburn, indigestion;
  • stomach pain, diarrhea;
  • back pain, joint pain, muscle pain; or
  • flu-like symptoms.

This is not a complete list of side effects
and others may occur. Call your doctor for medical advice about side effects.

What other drugs will affect risedronate?

Tell your doctor about all your current
medicines and any you start or stop using, especially:

  • aspirin;
  • iron supplements;
  • antacids, laxatives; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) –ibuprofen (Advil,
    Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and
    others.

This list is not complete. Other drugs may interact
with risedronate, including prescription and over-the-counter medicines,
vitamins, and herbal products. Not all possible interactions are listed in this
medication guide. Talk with your doctor about the best dosing schedule for your
other medicines.

Keyword: risedronate.

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