Olanzapine: Use & Side Effect

Olanzapine is an antipsychotic medication that affects chemicals in the brain.

It is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults and children who are at least 13 years old.

Olanzapine is sometimes used together with other antipsychotic medications or antidepressants.

Important Information

Olanzapine is not approved for use in psychotic conditions related to dementia. Olanzapine may increase the risk of death in older adults with dementia-related conditions.

Side Effect

Common side effects may include:

  • weight gain (more likely in teenagers), increased appetite;
  • headache, dizziness, drowsiness, feeling tired or restless;
  • problems with speech or memory;
  • tremors or shaking, numbness or tingly feeling;
  • changes in personality;
  • dry mouth, or increased salivation;
  • stomach pain, constipation; or
  • pain in your arms or legs.

Get emergency medical help if you have signs of an allergic reaction:

  • hives;
  • difficulty breathing;
  • swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
  • trouble speaking or swallowing;
  • swelling in your hands or feet;
  • confusion, unusual thoughts or behavior, hallucinations, or thoughts about hurting yourself;
  • sudden weakness or ill feeling, fever, chills, sore throat, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough;
  • signs of dehydration–feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • liver problems–upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • high blood sugar–increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or
  • severe nervous system reaction–very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Keyword: olanzapine.

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