Octreotide (injection): Uses & Side Effects

Octreotide (injection) is a man-made protein that is similar to a hormone in the body called somatostatin. Octreotide lowers many substances in the body such as insulin and glucagon(involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.

Octreotide is used to treat acromegaly. Octreotide is also used to reduce flushing episodes and watery diarrhea caused by cancerous tumors (carcinoid syndrome) or tumors called vasoactive intestinal peptide tumors (VIP adenomas).

Octreotide may also be used for purposes not listed in this medication guide.

Before taking this medicine

You should not use octreotide if you are
allergic to it.

To make sure you can safely use octreotide,
tell your doctor if you have any of these other conditions:

  • Diabetes;
  • Gallbladder disease;
  • Heart disease, high blood pressure, or heart rhythm disorder;
  • Thyroid problems;
  • Pancreatitis;
  • Liver disease; or
  • Kidney disease (or if you are on dialysis).

Octreotide is not expected to be harmful to
an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant
during treatment.

Using octreotide can affect certain hormones that may make it easier for you to get pregnant, even if you were unable to get pregnant before. Talk to your doctor about using birth control to avoid unwanted pregnancy.

It is not known whether octreotide passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Side effects

Call your doctor at once if you have:

  • Severe stomach pain or tenderness, severe constipation;
  • Slow or uneven heartbeats;
  • Severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
  • High blood sugar–increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss;
  • Low blood sugar–headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery; or
  • Underactive thyroid–extreme tired feeling, dry skin, joint pain or stiffness, muscle pain or weakness, hoarse voice, feeling more sensitive to cold temperatures, weight gain.

Common side effects may include:

  • Diarrhea, constipation;
  • Vomiting, upset stomach;
  • Bloating, gas;
  • Headache, dizziness; or
  • Pain when injecting the medicine.

Keyword: octreotide.

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