Lipodermatosclerosis: Symptom, Treatment


Lipodermatosclerosis, also called sclerosing panniculitis and hypodermitis sclerodermiform, is a skin and connective tissue disease. It is a form of lower extremity panniculitis and an inflammation of the layer of fat under the epidermis.

Types & Symptoms

There are mainly two types of lipodermatosclerosis: acute
lipodermatosclerosis and chronic lipodermatosclerosis. The symptoms
of lipodermatosclerosis vary between these two types.

Acute lipodermatosclerosis occurs without
local injury or preceding illness, and it affects mostly the middle aged. It is
characterized by the following symptoms:

  • A painful
    inflammation above the ankle in the inner leg which resembles cellulitis
  • The affected
    areas present to be red, scaly and tender

Chronic lipodermatosclerosis develops
gradually. It usually characterized by:

  • Pain
  • Localized thickening
  • Increased pigmentation
  • Edema
  • Varicose veins and leg ulcers


The exact causes for lipodermatosclerosis are still unknown. But the
following causes may be related to this condition:

  • Obesity
  • Venous disease, such as venous incompetence and venous hypertension
  • Tissue hypoxia
  • Leakage of proteins into the interstitium
  • Leukocyte activation


The diagnosis of lipodermatosclerosis is usually clinical based on observation. In some rare conditions, biopsy is required.


Common treatments for patients with lipodermatosclerosis

  • Compression Therapy

It is the main treatment, which uses compression stockings or tight bandaging on the affected surface.

  • Leg Elevation

  • Weight Loss

  • Vein Surgery

  • Fibrinolytic Agents

They use an enzymatic action to help dissolve the blood clots.

It is injected directly in the affected area.

  • Venous Ablation

It can help circulation for patients with this disease.

  • Clobetasol Propionate

It is usually used for reducing inflammation.

Keyword: lipodermatosclerosis.

Related Posts:

Lipodermatosclerosis: Causes, Symptoms and Treatments

What is Lipodermatosclerosis?

What is the Treatment for Lipodermatosclerosis?

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