Juvisync – simvastatin and sitagliptin

Juvisync contains a combination of simvastatin and sitagliptin.

Simvastatin is one of a group of statins. Simvastatin reduces levels of LDL cholesterol and triglycerides in the blood, while increasing levels of “good” cholesterol.

Sitagliptin is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating.

Juvisync is used in people with type 2 diabetes who also have high cholesterol or triglycerides (types of fat) in the blood. This medication is not for treating type 1 diabetes.

Juvisync is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.

Side effects include:

More Common

  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fainting
  • fast or irregular heartbeat
  • headache
  • increased hunger
  • nausea
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • unusual tiredness or weakness

Less Common

  • Bladder pain
  • bloody or cloudy urine
  • difficult, burning, or painful urination
  • dry mouth
  • flushed, dry skin
  • frequent urge to urinate
  • fruit-like breath odor
  • increased thirst
  • increased urination
  • loss of consciousness
  • lower back or side pain
  • stomachache
  • sweating
  • swelling
  • troubled breathing
  • unexplained weight loss
  • vomiting


  • Bloating
  • constipation
  • dark-colored urine
  • fever
  • indigestion
  • loss of appetite
  • muscle cramps or spasms
  • muscle pain, tenderness, wasting, or weakness
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • yellow eyes or skin

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