Gamma Globulin Test: Normal, High, and Low

The gamma globulin test measures the immunoglobin (immune gamma globulin) level in the blood. As the name suggests, immunoglobins are antibodies that fight off foreign threats in the immune system. Then, what does the gamma globulin test result mean?

Results and Meanings:

  • To make it clear, there are five types of immunoglobins: IgA, IgD, IgE, IgG, and IgM.
  • Therefore, there‚Äôre five sets of results in the gamma globulin test.
  • Normal Range:
    • IgA: 85-385 mg/dL
    • IgD: 8 mg/dL or lower
    • IgE: 4-590 mg/dL
    • IgG: 565-1770 mg/dL
    • IgM: 37-55 mg/dL
  • High levels indicate:
    • IgA: liver disorders or autoimmune disorders
    • IgD: periodic fever syndromes, certain genetic deficiency disorders, or allergies
    • IgE: asthma attack, parasitic infection, or atopic dermatitis
    • IgG: hepatitis, multiple sclerosis/MS, or a viral infection
    • IgM: parasitic infection, kidney damage, viral infection, or certain cancer
  • Low levels suggest:
    • IgA: kidney problems or cancer
    • IgE: muscle disease
    • IgG: kidney damage, leukemia, or other cancers
    • IgM: genetic immune system disorder or certain cancer


Keywords: gamma globulin; gamma globulin test; gamma globulin test result; gamma globulin test result interpretation; IgA; IgD; IgE; IgG; IgM

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