Factor Five Leiden & Blood Clots

Factor V Leiden, often called Factor Five Leiden, is a mutation of one of the clotting factors that can increase the risk of developing abnormal blood clots.

People with factor five Leiden may feel worried about developing abnormal clots. Actually, most people with factor five Leiden never develop abnormal clots. In people with factor five Leiden, the majority carry only one copy of the defective gene from either of the parents, it only slightly increases the risk of developing blood clots. Rarely people carry two copies of defective genes, one from each parents, this significantly increases the risk of developing blood clots.

Both men and women can have factor five Leiden. Women may have an increased tendency to develop blood clots during pregnancy or when taking the hormone estrogen.

Although most people with factor five Leiden doesn’t develop abnormal blood clots at all, in people who do, the abnormal clots can lead to long-term health problems or become life-threatening. If one has factor five Leiden and has developed blood clots, anticoagulant medications can lessen your risk of developing additional blood clots and help you avoid potentially serious complications.

The common blood clot is a blood clot in deep vein(DVT) in leg, and it may travel to the lung.

A DVT may not cause any symptoms. If signs and symptoms do occur, they can include pain, swelling, redness, warmth.

When a blood clot travels to the lung it’s called pulmonary embolism. This can be a life-threatening situation since the blood clot can block the blood flow. Signs and symptoms may include:

  • Sudden shortness of breath
  • Chest pain when breathing in
  • A cough that produces bloody or blood-streaked sputum
  • Rapid heartbeat


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