Esomeprazole is a proton pump inhibitor
that decreases the amount of acid produced in the stomach.
Esomeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Esomeprazole may also be given to prevent gastric ulcer caused by infection with Helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).
Esomeprazole is not for immediate relief of heartburn symptoms.
Before taking this medicine
Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.
You should not use this medicine if you are allergic to esomeprazole or to similar medicines such as lansoprazole, omeprazole, pantoprazole, rabeprazole, Dexilant, Nexium, Prevacid, Protonix, and others.
Tell your doctor if you have ever had:
- Severe liver disease;
- osteoporosis or low bone mineral density (osteopenia); or
- low levels of magnesium in your blood.
You may be more likely to have a broken bone
in your hip, wrist, or spine while taking a proton pump inhibitor long-term or
more than once per day. Talk with your doctor about ways to keep your bones
Ask a doctor before using this medicine if
you are pregnant or breast-feeding.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe stomach pain, diarrhea that is watery or bloody;
- seizure (convulsions);
- kidney problems–little or no urination, blood in your urine, swelling, rapid weight gain;
- low magnesium–dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or
- new or worsening symptoms of lupus–joint pain, and a skin rash on your cheeks or arms that worsens in sunlight.
esomeprazole long-term may cause you to develop stomach growths called fundic
gland polyps. Talk with your doctor about this risk.
If you use esomeprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.
effects may include:
- headache, drowsiness;
- mild diarrhea;
- nausea, stomach pain, gas, constipation; or
- dry mouth.