Clomipramine is a tricyclic antidepressant.
It affects chemicals in the brain that may be unbalanced. Clomipramine is used
to treat symptoms of obsessive-compulsive disorder (OCD) such as recurrent
thoughts or feelings and repetitive actions.
Clomipramine may also be used for purposes
not listed in this medication guide.
Ways to take clomipramine
Follow all directions on your prescription
label. Your doctor may occasionally change your dose. Do not take clomipramine
in larger or smaller amounts or for longer than recommended.
Take clomipramine with food to reduce
It may take up to 4 weeks before your
symptoms improve. Keep using the medication as directed and tell your doctor if
your symptoms do not improve after 4 weeks of treatment.
Call your doctor if your symptoms do not
improve, or if they get worse.
If you need surgery, tell the surgeon ahead
of time that you are using clomipramine. You may need to stop using the
medicine for a short time.
Do not stop using clomipramine suddenly, or
you could have unpleasant withdrawal symptoms. Ask your doctor how to safely
stop using clomipramine.
Store at room temperature away from
moisture and heat.
Get emergency medical help if you have
signs of an allergic reaction: hives; difficult breathing; swelling of your
face, lips, tongue, or throat.
Seek medical treatment if you have a
serious drug reaction that can affect many parts of your body. Symptoms may
include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches,
severe weakness, unusual bruising, or yellowing of your skin or eyes. This
reaction may occur several weeks after you began using clomipramine.
Report any new or worsening symptoms to
your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble
sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive,
restless, hyperactive (mentally or physically), more depressed, or have
thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
- blurred vision, tunnel vision, eye pain or swelling, or seeing halos
- rapid heart rate, tremors or shaking
- confusion, extreme fear, thoughts of hurting yourself
- painful or difficult urination
- a seizure (convulsions).
Seek medical attention right away if you
have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever,
sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of
coordination, nausea, vomiting, or diarrhea.
Common side effects may include:
- dry mouth, nausea, upset stomach, loss of appetite, constipation;
- feeling anxious, restless, dizzy, drowsy, or tired;
- sleep problems (insomnia);
- appetite or weight changes;
- memory problems, trouble concentrating;
- increased sweating, numbness or tingling;
- vision changes; or
- decreased sex drive, impotence, or difficulty having an orgasm.
Clomipramine: Uses & Side Effects