Clinical Trial – Urinary Markers of Fibrosis in Kidney Transplants – Kidney Failure

The purpose of this study is to determine whether urinary connective tissue growth factor can predict the onset of fibrosis in transplanted kidneys.
All renal allograft biopsies will be scored by a single renal pathologist according to the most recent Banff classification, blinded for the clinical parameters and timing of the biopsy. These rescoring data are directly entered in the dedicated Microsoft Access database (“Biopsy Database”).

Study Type : Observational [Patient Registry]
Estimated Enrollment : 180 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 24 Months
Official Title: Prospective Study of Urinary Connective Tissue Growth Factor and Related Pro-fibrotic Mediators as Potential Early Biomarkers of Progressive Renal Allograft Fibrosis in de Novo Kidney Recipients
Study Start Date : July 2015
Estimated Primary Completion Date : June 2017
Estimated Study Completion Date : June 2019
Contacts
Contact: Thomas Vanhove, MD +32 27055733 thomas.vanhove@uzleuven.be
Contact: Dirk Kuypers, MD, PhD +32 16344595 dirk.kuypers@uzleuven.be

 

ClinicalTrials.gov Identifier: NCT01982903

For enrollment please visit www.clinicaltrials.gov.

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