The purpose of this study is to determine whether urinary connective tissue growth factor can predict the onset of fibrosis in transplanted kidneys.
All renal allograft biopsies will be scored by a single renal pathologist according to the most recent Banff classification, blinded for the clinical parameters and timing of the biopsy. These rescoring data are directly entered in the dedicated Microsoft Access database (“Biopsy Database”).
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||180 participants|
|Target Follow-Up Duration:||24 Months|
|Official Title:||Prospective Study of Urinary Connective Tissue Growth Factor and Related Pro-fibrotic Mediators as Potential Early Biomarkers of Progressive Renal Allograft Fibrosis in de Novo Kidney Recipients|
|Study Start Date :||July 2015|
|Estimated Primary Completion Date :||June 2017|
|Estimated Study Completion Date :||June 2019|
|Contact: Thomas Vanhove, MD||+32 27055733||[email protected]|
|Contact: Dirk Kuypers, MD, PhD||+32 16344595||[email protected]|
For enrollment please visit www.clinicaltrials.gov.