Chymotrypsin Test – Normal, High, Low

Mean chymotrypsin is high at a pH greater than 7. Between pH 6 and 7 the mean value drops to 8.6 U/g stool and below pH 6 mean chymotrypsin is in the abnormal range.

Hence, low values for chymotrypsin may be due to lower pH (less than 6) in healthy control subjects.

  • A positive result, indicating the presence of chymotrypsin in the stool, is normal. Chymotrypsin is present in the stool of healthy individuals.
  • A negative result may mean that the person tested has pancreatic insufficiency. It is not diagnostic, but it does indicate that further testing may be indicated.

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