Cabozantinib is used to treat advanced
kidney cancer, or thyroid cancer that has spread to other parts of the body. Cabozantinib
is also used to treat liver cancer in people who have been previously treated
with sorafenib (Nexavar).
should I take cabozantinib?
Follow all directions on your prescription label
and read all medication guides or instruction sheets. Use the medicine exactly
Do not use cabozantinib tablets in place of
cabozantinib capsules. Take only the pill form your doctor has prescribed.
Avoid medication errors by always checking the medicine you receive at the
Take cabozantinib on an empty stomach, at
least 1 hour before or 2 hours after you eat anything.
Do not take this medicine with food.
Take this medicine with a full glass of
Do not crush, chew, or break a tablet, and
do not open a capsule. Swallow the pill whole.
Your blood pressure will need to be checked
If you need surgery or dental work, stop
taking cabozantinib at least 28 days ahead of time.
If you have stopped taking cabozantinib for
any reason, talk with your doctor before you start taking it again.
Store at room temperature away from
moisture and heat.
You should not use cabozantinib if you are
allergic to it.
Tell your doctor if you have:
- an open wound on your skin (or a wound that is still healing);
- bleeding problems (such as bloody or tarry stools, or coughing up
blood or vomit that looks like coffee grounds);
- high blood pressure;
- liver disease;
- a pre-existing dental problem.
You may need to have a negative pregnancy
test before starting this treatment.
Cabozantinib may harm an unborn baby. Use
effective birth control to prevent pregnancy while you are using cabozantinib
and for at least 4 months after your last dose. Tell your doctor if you think
you might be pregnant.
You should not breast-feed while using this
medicine, and for at least 4 months after your last dose.
Get emergency medical help if you have
signs of an allergic reaction: hives; difficult breathing; swelling of your
face, lips, tongue, or throat.
Cabozantinib may cause a perforation (a
hole or tear) or a fistula (an abnormal passageway) within your stomach or
intestines. Call your doctor if you have severe stomach pain, or if you feel
like you are choking and gagging when you eat or drink.
Call your doctor at once if you have:
- severe or ongoing vomiting or diarrhea;
- bloody or tarry stools, cough with bloody mucus or vomit that looks
like coffee grounds;
- heavy menstrual bleeding, or any other bleeding that will not stop;
- pain, tenderness, redness, swelling, blistering, or peeling skin on
the palms of your hands or the soles of your feet;
- confusion, headache, vision changes, thinking problems;
- a seizure;
- a light-headed feeling, like you might pass out;
- jaw pain, tooth pain, mouth sores;
- heart attack symptoms–chest pain or pressure, pain spreading to
your jaw or shoulder, sweating;
- signs of a stroke–sudden numbness or weakness (especially on one
side of the body), sudden severe headache, slurred speech, problems with vision
- signs of a blood clot–chest pain, cough, trouble breathing,
swelling or warmth in your arms or legs.
Your future doses of cabozantinib may be
delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- nausea, vomiting, stomach pain, loss of appetite;
- diarrhea, constipation;
- mouth sores or redness, changes in your sense of taste;
- feeling tired;
- weight loss;
- abnormal liver function tests or other blood tests.
Always consult your healthcare provider to
ensure the information displayed on this page applies to your personal