Apo A Test – Reference Range

The normal value of apolipoprotein A1 is different to men and women.

  • Male: > 120 mg/dl
  • Female: > 140 mg/dl

Apolipoprotein A-I (apo A-I) is a protein that has specific roles in the transportation and metabolism of lipids and is the main protein component in high-density lipoprotein (HDL, the “good cholesterol“).

This test measures the amount of apo A-I in the blood.

Low levels of apo A-I are usually associated with low levels of HDL and impaired clearance of excess cholesterol from the body. Low levels of apo A-I, along with high concentrations of apo B, are associated with an increased risk of cardiovascular disease.

High levels of apo A-I is considered protective and can be independent of HDL levels. There are some genetic disorders that lead to deficiencies in apo A-I (and therefore to low levels of HDL).

People with these disorders tend to have abnormal lipid levels, including high levels of low-density lipoprotein (LDL – the “bad cholesterol“). Frequently, they have accelerated rates of atherosclerosis. These genetic disorders are primary causes of low apo A-I.

Keywords: Apo A; Apo A-I; apolipoprotein A-I

Leave a Reply