Angiotensin-Converting Enzyme (ACE) Inhibitors: Uses & Side Effects

Angiotensin-converting enzyme (ACE) inhibitors help relax blood vessels. ACE inhibitors prevent an enzyme in your body from producing angiotensin II, a substance in your body that narrows your blood vessels and releases hormones that can raise your blood pressure.

Examples of ACE inhibitors:

Many ACE inhibitors are available. You should choose the most proper one for you according to your own health condition. ACE inhibitors include:

  • Benazepril (Lotensin)
  • Captopril
  • Enalapril (Vasotec)
  • Fosinopril
  • Lisinopril (Prinivil, Zestril)
  • Moexipril
  • Perindopril (Aceon)
  • Quinapril (Accupril)
  • Ramipril (Altace)
  • Trandolapril (Mavik)


ACE inhibitors are used to treat or improve the following conditions:

  • High blood pressure
  • Coronary artery disease
  • Heart failure
  • Diabetes
  • Certain chronic kidney diseases
  • Heart attacks
  • Scleroderma
  • Migraines

Side effects:

Although ACE inhibitors do not often cause side effects, there are still some possible side effects. They include:

  • Dry cough
  • Increased blood-potassium level (hyperkalemia)
  • Fatigue
  • Dizziness
  • Headaches
  • Loss of taste

In addition, people of African heritage and smokers are more likely than other groups to have swell in some areas of tissues Women who plan to get pregnant need to be cautious when taking ACE inhibitors because birth defects may be caused. Therefore, consult your doctor for professional advice if you are worried about the effect of ACE inhibitors.

Keywords: Angiotensin-converting enzyme (ACE) inhibitors

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