Age 50-69, Aspirin Prevents CVD & Colon Cancer

The U.S. Preventive Services Task Force (USPSTF) released an updated guidance in 2016 for Aspirin use to prevent cardivascular disease and colorectal cancer. According to the guidance, adults aged 50 to 69 can benefit from taking low-dose aspirin daily in the prevention of heart disease and colon cancer.

This table presents the content.

Population Recommendation Grade
Adults ages 50 to 59 years The USPSTF recommends low-dose aspirin use for the primary prevention of cardiovascular disease (CVD) and colorectal cancer in adults ages 50 to 59 years who have a 10% or greater 10-year CVD risk, are not at increased risk for bleeding, have a life expectancy of at least 10 years, and are willing to take low-dose aspirin daily for at least 10 years. B

Moderately certainty

Adults ages 60 to 69 years The decision to use low-dose aspirin to prevent CVD and colorectal cancer in adults ages 60 to 69 years who have a greater than 10% 10-year CVD risk should be an individual one. Persons who are not at increased risk for bleeding, have a life expectancy of at least 10 years, and are willing to take low-dose aspirin daily for at least 10 years are more likely to benefit. Persons who place a higher value on the potential benefits than the potential harms may choose to use low-dose aspirin. C

Selectively recommend

Adults younger than age 50 years The current evidence is insufficient to assess the balance of benefits and harms of aspirin use to prevent CVD and colorectal cancer in adults younger than age 50 years. I

Insufficient evidence

Adults age 70 years and older The current evidence is insufficient to assess the balance of benefits and harms of aspirin use to prevent CVD and colorectal cancer in adults age 70 years and older. I

Insufficient evidence

 

According to the guidance, aspirin intake is most helpful in preventing CVD and colorectal cancer for the age group 50-59 years. The risk of aspirin is that it elevates the chance of bleeding. For people who has a low risk of bleeding, taking low-dose aspirin each day for 10 years is helpful.

For the age group 60-69, people who match the following conditions can choose to take low-dose aspirin daily if you’re willing to, it still helps.

  1. life expectancy is more than 10 years
  2. 10-year CVD risk is higher than 10%
  3. not at elevated risk of bleeding when take low-dose aspirin

The daily use of aspirin is not recommended to the age group below 50 or above 70, because there’re not sufficent evidence to provide its effectiveness.

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