The normal reference range for quantitative acetoacetate assays measured by gas chromatography is:
Normal range (plasma/serum): 5-30 µg/mL (conventional units).
Semiquantitative methods, although nonspecific for acetoacetate, are frequently used to determine the presence of ketone bodies (acetone and acetoacetate) in urine and blood and are discussed in Ketones.
- If blood ketone levels are increased, then the person has some degree of ketosis or ketoacidosis.
- If levels are low or normal, then the person either does not have excess ketone production or the ketone body that is elevated is not being detected by the test method used.